HCM and septal myectomy evidence comparison · Decision guide

HCM and septal myectomy surgeon rankings: experience, methods and results

8 surgical teams · 6 clinical studies · expertise, methods and reported experience.

Research by Yevhenii Kozlov · Co-Founder of BookimedUpdated 8 October 2026Sources linked throughout

At a glance

Compare hcm and septal myectomy surgeons and programmes by the operations they offer, relevant experience and clinical results. Each team has one card, with its studies grouped underneath. Reported practice totals carry their source; study samples stay beside their own results.

Follow-up stays visible

Early perioperative outcomes and multi-year observation answer different clinical questions.

A shortlist, not a success leaderboard

Different case selection and outcome definitions prevent a valid best-to-worst surgical outcome ranking.

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HCM and septal myectomy surgeons and specialist teams

Compare reported surgical experience

Positions use published operation counts within the same procedure, reporting period and attribution. “+” is a reported minimum. Personal operations, participation and programme totals have separate lists. A dash means open-ended counts do not establish an exact place. The lists compare experience, not safety or suitability.

Programme operations · 2024 · septal myectomies

2 specialists or programmes with comparable public figures in this researched shortlist. Source dates and the exact operation scope are shown beside each figure.

1
Yong Cui / Zhejiang Provincial People’s HospitalRight infra-axillary modified-Morrow myectomies. This technique-specific count is a minimum for the programme’s total myectomy activity; other approaches are not included.
250+Calendar year 2024 · published 2025-01-31 · counting date 2024-12-31Source ↗ · read 2026-10-08
2
Nicholas Smedira / Cleveland ClinicProgramme total across septal approaches, including operations with associated procedures.
201Calendar year 2024 · published 2025-08-27 · counting date 2024-12-31Source ↗ · read 2026-10-08

Programme operations · Cumulative reported experience · septal myectomies

2 specialists or programmes with comparable public figures in this researched shortlist. Source dates and the exact operation scope are shown beside each figure.

—
Yong Cui / Zhejiang Provincial People’s HospitalHCM myectomy programme using an underarm route that preserves the breastbone.
1,000+Cumulative; counting cutoff not statedSource ↗ · read 2026-10-08
—
Daniel G. Swistel / NYU LangoneNYU programme total; distinct from any one surgeon’s career experience.
600+Cumulative; counting cutoff not statedSource ↗ · read 2026-10-08

Cards follow the selected procedure’s default experience comparison above. Providers without a comparable public count retain their clinical profiles without a numbered position.

Specialist expertiseHCM / myectomy
Yong Cui — official portrait

Yong Cui

Zhejiang Provincial People’s Hospital

#1 · Programme operations · 2024 · septal myectomies · among 2 with comparable public figures

250+septal myectomiesProgramme operations

Calendar year 2024 · published 2025-01-31 · counting date 2024-12-31

Right infra-axillary modified-Morrow myectomies. This technique-specific count is a minimum for the programme’s total myectomy activity; other approaches are not included.

心有“勇”术|崔勇:寻道创新,微步致远 ↗

Right infra-axillary transaortic myectomy with documented subvalvular work.

Papillary resection in 72/148 (48.6%); chordal resection in 93/148 (62.8%); papillary reorientation in 15/148 (10.1%). Procedures overlap.

Sources: An innovative minimally invasive approach for HOCM: transaortic septal myectomy via right infra-axillary incision · Yong Cui practice profile

1,000+ septal myectomies

Programme operations · Cumulative; counting cutoff not stated

HCM myectomy programme using an underarm route that preserves the breastbone.

MESM programme / Yong Cui ↗ · source read 2026-10-08
5,000+ Minimally invasive cardiac operations across conditions

Programme operations · Cumulative; counting cutoff not stated

Minimally invasive heart operations across conditions since 2018; this is broader than HCM.

Yong Cui practice overview ↗ · source read 2026-10-08
2 clinical studies · methods, results and risks

Right infra-axillary transaortic myectomy with documented subvalvular work.

148 patients in this study

September 2021–July 2023 · published 2024

Papillary resection in 72/148 (48.6%); chordal resection in 93/148 (62.8%); papillary reorientation in 15/148 (10.1%). Procedures overlap.

Results: Mean peak LVOT gradient 85.1 → 11.7 mmHg after surgery. 1/148 in-hospital death; 8/148 permanent pacemakers; no conversion to sternotomy reported.

Follow-up: Numerical follow-up duration was not specified in the inspected report.

Study context: Zhejiang Provincial People’s Hospital study, with Yong Cui as senior/corresponding author. Selected single-centre approach series without a sternotomy control group. Pacemaker risk is affected by baseline conduction abnormalities. This is the earlier modified-Morrow series, not the newer 100-patient MESM series.

Sources: An innovative minimally invasive approach for HOCM: transaortic septal myectomy via right infra-axillary incision · Yong Cui practice profile

Electro-septal sculpting through a 4–5 cm right infra-axillary incision.

100 patients in this study

November 2023–May 2024 · print publication 2026

A distinct newer technique cohort. The practice site describes a long electrocautery instrument; the study abstract reports aortic cross-clamping.

Results: Mean peak LVOT gradient 85.8 → 8.4 mmHg after surgery. 4/100 pacemakers; no in-hospital death, iatrogenic VSD or sternotomy conversion reported.

Follow-up: Early postoperative outcomes; long-term duration unavailable in the abstract.

Study context: Zhejiang Provincial People’s Hospital study, with Yong Cui as senior/corresponding author. Abstract-only review. Do not sum this cohort with other publications or the practice website’s lifetime claims. Zero observed deaths does not mean zero risk.

Sources: Minimally Invasive Electro Septal Myectomy for HOCM Through a Right Infra-Axillary Incision · MESM: minimally invasive electro septal myectomy

Specialist expertiseHCM / myectomy
Nicholas Smedira — official portrait

Nicholas Smedira

Cleveland Clinic

#2 · Programme operations · 2024 · septal myectomies · among 2 with comparable public figures

201septal myectomiesProgramme operations

Calendar year 2024 · published 2025-08-27 · counting date 2024-12-31

Programme total across septal approaches, including operations with associated procedures.

Cleveland Clinic 2024 HOCM data highlights ↗

A broad surgical series that includes mitral and subvalvular correction.

522 operations combined myectomy with mitral or subvalvular intervention. Those patients had thinner septums on average than patients without mitral intervention.

Sources: Surgical management of LVOT obstruction in a specialized HOCM center · Nicholas Smedira, MD — Cleveland Clinic

2,000+ septal myectomies

Personal participation · Cumulative participation; myectomy-specific start and cutoff not stated

The institutional profile attributes participation in septal myectomies to Smedira; it does not allocate all cases to him as sole operator.

Dr. Nicholas Smedira, MD – Cleveland, OH – Cardiac Surgery – Request Appointment ↗ · source read 2026-10-08
3,500+ septal myectomies

Programme operations · 2002–2021; exact boundary dates not specified

Cleveland programme experience across 2002–2021, described by Milind Desai in an official clinical discussion. It is separate from Smedira’s personal participation count.

Surgical Myectomy for Hypertrophic Cardiomyopathy ↗ · source read 2026-10-08
1 clinical study · methods, results and risks

A broad surgical series that includes mitral and subvalvular correction.

1530 myectomy-containing operations in this study

2005–2015 · study published 2019

522 operations combined myectomy with mitral or subvalvular intervention. Those patients had thinner septums on average than patients without mitral intervention.

Results: Operative mortality 0.38% in the full 1,559-operation LVOTO cohort. Complete-block pacemakers: 4.2% of the reported 1,334-patient denominator.

Follow-up: Perioperative outcomes in the primary abstract; no comparable long-term duration extracted.

Study context: Smedira is a currently listed myectomy specialist and study coauthor. The primary abstract says one surgeon, but does not name that operator. These are programme-study results. 1,530 is derived from 586 isolated + 522 with mitral/subvalvular work + 422 with other procedures. Another 29 operations were mitral-only. This is not current annual volume.

Sources: Surgical management of LVOT obstruction in a specialized HOCM center · Nicholas Smedira, MD — Cleveland Clinic

Specialist expertiseHCM / myectomy
Daniel G. Swistel — official portrait

Daniel G. Swistel

NYU Langone

700+septal myectomiesPersonal operations

Cumulative; counting cutoff not stated

Personal experience with septal myectomy; associated mitral leaflet and papillary-muscle anatomy may also be treated.

NYU Langone: Daniel Swistel surgical experience ↗

HCM myectomy and mitral valve repair

Daniel Swistel directs HCM surgery at NYU Langone. His published resect–plicate–release approach combines septal muscle removal with selected leaflet shortening and release of abnormal papillary attachments.

Sources: Resect–plicate–release · 77-patient study (2015) · NYU Langone · Daniel Swistel · NYU Langone · HCM programme

600+ septal myectomies

Programme operations · Cumulative; counting cutoff not stated

NYU programme total; distinct from any one surgeon’s career experience.

NYU HCM programme ↗ · source read 2026-10-08
Specialist expertiseHCM / myectomy

Hassan Rastegar

historical Tufts series

1,000+septal myectomiesPersonal operations

Cumulative; counting cutoff not stated · published 2023-02-20

Career experience reported by BIDMC in 2023; the linked Tufts study describes an earlier programme.

BIDMC: Rastegar lifetime surgical experience ↗

Explicitly attributed individual-operator experience with longer-term follow-up.

All 507 myectomies are attributed to Rastegar. The analysis excludes 25 patients with severe aortic stenosis.

Sources: Results of surgical septal myectomy for obstructive HCM: the Tufts experience

1 clinical study · methods, results and risks

Explicitly attributed individual-operator experience with longer-term follow-up.

482 patients analysed; 507 operated in this study

2003–2016 · study published 2017

All 507 myectomies are attributed to Rastegar. The analysis excludes 25 patients with severe aortic stenosis.

Results: 4/482 operative deaths; 43/482 complete-heart-block pacemakers. The paper’s lower adjusted pacemaker percentage is not the all-patient rate.

Follow-up: Mean clinical follow-up 3.2 years. Estimated survival: 94% at 5 years and 91% at 10 years; not every patient was followed for 10 years.

Study context: Individual operator named in the primary study. Historical benchmark; current appointment and availability were not established in this review. Different selection and follow-up denominators apply. Older outcomes are useful for understanding durability, not a present-day booking recommendation.

Sources: Results of surgical septal myectomy for obstructive HCM: the Tufts experience

Specialist expertiseHCM / myectomy

Joseph A. Dearani

Mayo Clinic Rochester

Nearly 5,000septal myectomiesProgramme operations

Cumulative; counting cutoff not stated

Nearly 5,000 programme myectomies since the programme began in 1961. The approximate total is shown without assigning a numbered place.

Mayo 2025 Cardiovascular Surgery Annual Report ↗

HCM and congenital heart surgery

Joseph Dearani’s Mayo practice spans HCM, Ebstein anomaly, congenital surgery and complex reoperations. Mayo’s selected apical-myectomy research addresses a different problem from routine basal septal obstruction.

Sources: Mayo Clinic · HCM treatment options · Mayo · 67 patients with apical aneurysm repair · Mayo Clinic · Joseph Dearani

203 septal myectomies

Programme operations · 2024-06–2025-06

Mayo Rochester adult and paediatric programme; the report uses June 2024–June 2025, not a calendar year.

Mayo 2025 Cardiovascular Surgery Annual Report ↗ · source read 2026-10-08
About 500 Apical myectomies

Programme operations · Cumulative; counting cutoff not stated

Apical myectomies are part of the broader Mayo programme total, not an additional count.

Mayo 2025 Cardiovascular Surgery Annual Report ↗ · source read 2026-10-08
Specialist expertiseHCM / myectomy
Portrait of Professor Paolo Ferrazzi

Paolo Ferrazzi and colleagues

Policlinico di Monza

400+septal myectomiesPersonal operations

Cumulative; counting cutoff not stated · source edition 2022-06-29

Personal myectomy experience in a June 2022 hospital brochure; includes expertise in mitral secondary-chordal work.

Policlinico di Monza HCM brochure ↗

Myectomy plus cutting selected secondary mitral chordae

Addresses thickened or retracted secondary chordae alongside septal muscle.

Sources: Ferrazzi et al. · JACC 2026 · 350 patients

1 clinical study · methods, results and risks

Myectomy plus cutting selected secondary mitral chordae

350 consecutive patients in the reported centre cohort in this study

Published June 2026 · operations over a five-year period

Addresses thickened or retracted secondary chordae alongside septal muscle.

Results: Follow-up available for 344 patients; latest NYHA classes I / II / III: 271 / 65 / 8. Reported six-year overall survival was 96%, including two in-hospital deaths.

Follow-up: Median 5.6 years (interquartile range 4.2–6.3).

Study context: Single-centre team cohort; Ferrazzi is first author. It is not his personal lifetime count. Observational series. Population-matched survival is not a comparison with other surgeons or methods. Primary abstract reviewed.

Sources: Ferrazzi et al. · JACC 2026 · 350 patients

Specialist expertiseHCM / myectomy

Xiang Wei research team

Tongji Hospital

Transapical beating-heart myectomy: a different access route and instrument strategy.

The post-learning-curve series uses a transapical approach. It is distinct from Cui’s right infra-axillary, transaortic MESM.

Sources: TA-BSM for obstructive HCM: Lessons Learned After the Learning Curve Period · Transapical beating-heart septal myectomy for HCM patients with midventricular obstruction

Broader practice and technique context
1,000+ TA-BSM for HCM

Multiple centres · Cumulative; counting cutoff not stated · published 2024-12-23 · counting date 2024-12-23

Adoption across 15 hospitals; this count describes the technique’s network, not Xiang Wei’s personal or Tongji-only volume.

HUST academic advances: Xiang Wei TA-BSM programme ↗ · source read 2026-10-08
1 clinical study · methods, results and risks

Transapical beating-heart myectomy: a different access route and instrument strategy.

418 patients in this study

January 2023–January 2024 · published 2025

The post-learning-curve series uses a transapical approach. It is distinct from Cui’s right infra-axillary, transaortic MESM.

Results: 91.1% met the defined 3–6-month composite: resting/provoked LVOT gradient below 30/50 mmHg and MR no worse than 2+. 1/418 died within 30 days; 10/418 needed pacemakers.

Follow-up: Median 310 days (IQR 207–408).

Study context: Team cohort with Xiang Wei as senior/corresponding author; the abstract does not establish that he operated on every patient. Primary abstract reviewed; detailed exclusions require full text. Also reported: 3 apical tears, 3 mitral injuries and 2 transient ischemic strokes. The 91.1% definition is not a general “success rate”.

Sources: TA-BSM for obstructive HCM: Lessons Learned After the Learning Curve Period · Transapical beating-heart septal myectomy for HCM patients with midventricular obstruction

What the comparison can and cannot establish

Potential advantages

  • Procedure-specific evidence makes differences in technique, anatomy and observation period visible before comparing teams.

Trade-offs and limits

  • These studies are not a matched comparison of the listed surgeons. Personal treatment suitability and risk require clinical assessment.

How to read the comparison

Recruitment dates describe when operations took place; follow-up describes how long patients were observed. Both remain visible beside each study.

Complication and outcome definitions differ. Counts are not pooled, programme cohorts are not automatically personal surgeon totals, and smaller incisions are not treated as proof of better outcomes.

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