Replacement: symptoms, function and procedure risks
In the 400-patient TRISCEND II randomized trial, replacement plus medical therapy improved the one-year composite outcome, mainly through symptoms and quality of life. Severe bleeding and new pacemakers were more frequent with replacement.
How to interpret this: Device-specific, selected-patient, multicentre evidence. It does not establish a survival advantage or Kodali-specific success rate, and is not a comparison of replacement with tricuspid repair or surgery.
Sources: Transcatheter Valve Replacement in Severe Tricuspid Regurgitation.