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Los Angeles, United States · Robotic mitral repair measured by anatomy and durability

Research by Yevhenii Kozlov · Co-Founder of BookimedUpdated 8 October 2026Sources linked throughout

At a glance

Cedars-Sinai’s Smidt programme has studied both an expanding robotic team and the durability of complex Barlow repair. Its evidence distinguishes getting a valve repaired from preventing recurrent leakage years later.

Team experience

A 1,410-operation registry involved four surgeons; 1,234 of 1,237 degenerative valves were repaired.

Sources: Eliminating the learning curve in robotic mitral valve repair: Results from 1400 patients.

Complex anatomy analysed separately

The Barlow analysis covered 111 patients within a 924-patient degenerative-mitral registry.

Sources: Robotic repair for Barlow mitral regurgitation: Repairability, safety, and durability.

Five-year Barlow endpoint

Survival free from greater-than-moderate leakage was reported at 92%, with an 80.2%–98.1% confidence interval.

Sources: Robotic repair for Barlow mitral regurgitation: Repairability, safety, and durability.

Joanna Chikwe discussing heart imaging with a colleague
Joanna Chikwe in a clinical discussion, in a photograph published by the Smidt Heart Institute. Photo: Cedars-Sinai. · Image source ↗
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Los Angeles · United States

cardiac surgeon

Joanna Chikwe →

Joanna Chikwe chairs cardiac surgery at Cedars-Sinai’s Smidt Heart Institute. Her coauthored studies distinguish routine degenerative prolapse from complex Barlow disease and follow recurrent leakage as well as repair completion.

Sources: Eliminating the learning curve in robotic mitral valve repair: Results from 1400 patients. · Robotic repair for Barlow mitral regurgitation: Repairability, safety, and durability.

Procedure-specific research

Read alongside Joanna Chikwe’s profile →

A programme of 1,410 robotic mitral operations

Chikwe was first author of a 2005–2023 registry study involving four surgeons. Of 1,237 degenerative cases, 1,234 were repaired; overall operative mortality was 0.3%. The report describes favourable outcomes as subsequent surgeons joined an experienced programme.

How to interpret this: Historical institutional results across four surgeons, not 1,410 operations by Chikwe. Most degenerative cases had isolated P2 prolapse; results should not be assumed for every complex valve.

Sources: Eliminating the learning curve in robotic mitral valve repair: Results from 1400 patients.

Read alongside Joanna Chikwe’s profile →

Barlow durability measured separately

The Barlow analysis reported 92% survival free from greater-than-moderate regurgitation at five years, with a wide 95% confidence interval of 80.2%–98.1%.

How to interpret this: This endpoint differs from freedom from reoperation and from absence of any residual regurgitation. Nonrandomized programme follow-up.

Sources: Robotic repair for Barlow mitral regurgitation: Repairability, safety, and durability.

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