PFA for persistent AF: benefits, evidence and treatment planning

PFA is a treatment option for persistent AF as well as paroxysmal AF. In ADVANTAGE AF, which treated persistent AF with FARAPULSE, 85.3% were free from symptomatic AF at one year; the stricter primary effectiveness estimate was 63.5%. The study treated the pulmonary veins and posterior wall and had no thermal-ablation control group, so it does not show that PFA is better than thermal ablation.

Read more

PFA vs heat or freezing for AF

Pulsed field ablation (PFA) uses electrical pulses instead of heat or freezing. It may limit damage to nearby tissues, but it has not been proved the best option for everyone. For AF episodes that stop within seven days, one large trial found similar one-year results—not a higher success rate with PFA.

Read more