Brain and spinal cord tumors: surgery and treatment options

Decision guide

Brain and spinal cord tumors: surgery and treatment options

Brain and spinal tumours: 5 methods with evidence, selected by diagnosis. For recurrent glioblastomas: progression-free survival: 25% (laser interstitial thermal therapy); 6 months. Bookimed lists 29 surgeons at 25 clinics in 6 countries; packages from 1,360 USD. StudyPackage

Research project led by Yevhenii Kozlov · Co-Founder of BookimedUpdated 21 October 2026Sources linked throughout
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How surgery works and how approaches differ

For a tumor growing within the spinal cord, surgery aims to remove tumor tissue while preserving nerve function. Electrical monitoring during the operation checks pathways involved in movement and sensation. Combining movement and sensory monitoring can identify neurological problems more accurately than either type alone. For tumors inside the spinal covering but outside the cord itself, minimally invasive and conventional open approaches have been compared. These are different anatomical situations, not interchangeable treatment choices. In meningioma surgery, fluorescence guidance uses a substance called 5-ALA to help make tumor tissue visible during removal.

Sources (4)

Methods and what the numbers show

Other methods with evidence

Method What it is What the numbers show
Removal of all visible tumour The surgeon aims to remove all tumour that can be seen during the operation or on imaging. — WHO grade III malignant meningioma
  • overall survival: 0.54 HR (gross total resection) vs (subtotal resection); n=2,208 patients (study) [2]
Heating tumour tissue with a laser A laser probe placed inside the tumour heats and destroys targeted tissue. — recurrent glioblastomas
  • progression-free survival: 25% (laser interstitial thermal therapy); 6 months [3]
Focused radiation treatment Focused beams deliver radiation to a defined tumour target.
    Precisely targeted radiation treatment Stereotactic imaging guides focused radiation beams to the tumour.
      Complete tumour removal The surgeon aims to remove the whole tumour rather than leave a visible remainder. — WHO grade III malignant meningioma
      • overall survival: 0.54 HR (gross total resection) vs (subtotal resection); n=2,208 patients (study) [2]

      When surgery may help and what alternatives to discuss

      One treatment discussion concerns how to reach the tumor while limiting disturbance of nearby nerves. For spinal tumors outside the cord but inside its covering, minimally invasive surgery is an alternative to an open approach. For adults having a tumor removed through the back of the neck without spinal fixation, younger age, removal of bone at the second neck vertebra and surgery across more vertebral levels are associated with later spinal deformity or instability. Stabilizing the spine during tumor removal may therefore be considered in selected patients.

      Sources (2)

      Expected outcomes and limits of the evidence

      For tumors outside the spinal cord but inside its covering, a 2022 review compared 149 patients having minimally invasive surgery with 153 having open surgery across seven studies. During surgery and the hospital stay, the minimally invasive group had less blood loss, shorter operations and shorter stays. Rates of complete removal and surgical or medical complications were similar. These findings concern that tumor location and do not establish the better approach for tumors growing within the cord.

      Evidence about tranexamic acid, a medicine used to reduce surgical bleeding, is mixed for meningioma removal. A 2024 review covering 781 patients found lower blood loss during surgery, with substantial variation between studies. A separate 2024 randomized trial of 600 patients having meningioma surgery in the upper part of the brain found no significant reduction in bleeding with a single dose. Neither comparison establishes long-term tumor control.

      Sources (3)

      Risks to discuss with your surgeon

      Surgery within the spinal cord carries a risk of problems with movement or sensation after the operation. Monitoring studies distinguish temporary from persistent movement problems; electrical monitoring helps detect risk rather than guaranteeing preserved function.

      Seizures are one early risk after meningioma removal. In a randomized trial involving 600 patients having surgery for a meningioma in the upper part of the brain, seizures occurred within seven days in 13 of 300 patients given tranexamic acid (4.3%) and 11 of 300 given saline (3.7%). Those figures describe the trial groups, not an individual’s predicted risk. Other reported problems after meningioma surgery include headache and leakage of cerebrospinal fluid, the fluid surrounding the brain and spinal cord.

      Sources (4)

      Recovery and follow-up care

      Early recovery after meningioma surgery can involve monitoring headaches and leakage of the fluid surrounding the brain. After tumor removal through the back of the neck without spinal fixation, follow-up also needs to check for changes in spinal alignment and stability. This is particularly relevant after surgery involving the second neck vertebra or several vertebral levels, and in younger adults.

      Sources (2)

      Explore surgery and care teams

      Specialists and their operations

      Israel · 4 entries
      Specialist Clinic Operations and experience Ask about treatment
      Zvi Ram Sourasky Medical Center (Ichilov)

      Tel Aviv, Israel

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 1989

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      Professor Shimon Rochkind Sourasky Medical Center (Ichilov)

      Tel Aviv, Israel

      Removal of spinal cord tumor

      In practice since 1979

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      Shlomi Constantini Sourasky Medical Center (Ichilov)

      Tel Aviv, Israel

      Removal of spinal cord tumor

      In practice since 1984

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      Anton Wohl Sheba Medical Center

      Ramat Gan, Israel

      Removal of meningioma

      In practice since 2004

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      Germany · 1 entries
      Specialist Clinic Operations and experience Ask about treatment
      Ralf Buhl Medical Center in Solingen

      Solingen, Germany

      Removal of spinal cord tumor

      In practice since 1998

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      Spain · 2 entries
      Specialist Clinic Operations and experience Ask about treatment
      Bartolome Oliver Centro Médico Teknon

      Barcelona, Spain

      Removal of meningioma

      In practice since 1976

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      Nnamdi Elenwoke Centro Médico Teknon

      Barcelona, Spain

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2007

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      Turkey · 1–12 of 19 entries
      Specialist Clinic Operations and experience Ask about treatment
      Baran Yılmaz Istinye University Liv Hospital Bahcesehir

      Istanbul, Turkey

      Removal of spinal cord tumor Ask about treatment
      Salih Murat Imer Istanbul Florence Nightingale Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 1985

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      Erkan Kaptanoglu Estexper Clinic

      Istanbul, Turkey

      Removal of spinal cord tumor

      In practice since 1992

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      Ahmet Karkucak Büyük Anadolu Hospitals (BAH International)

      Istanbul, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2019

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      Ramazan Sari Istanbul Florence Nightingale Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2004

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      Melih Uc Valued Med Hub Hospitals

      Istanbul, Turkey

      Removal of spinal cord tumor

      In practice since 2007

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      Hasan Ozgur Ozdemir Medical Park Antalya Hospital Complex

      Antalya, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2002

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      Ramazan Uyar Medical Park Antalya Hospital Complex

      Antalya, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 1991

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      Ertugrul Pinar Hisar Hospital Intercontinental

      Istanbul, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2016

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      Tuncay Kaner Medical Park Bahcelievler Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor

      In practice since 1989

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      Kenan Kibici Medical Park Bahcelievler Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 1993

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      Ibrahim Ziyal Memorial Göztepe Hospital

      Istanbul, Turkey

      Removal of meningioma

      In practice since 1996

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      Turkey · 13–19 of 19 entries
      Specialist Clinic Operations and experience Ask about treatment
      Mehmet Aydogan Memorial Şişli Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor

      In practice since 1950

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      Ahmet Hilmi Kaya Anadolu Medical Center

      Istanbul, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 1996

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      Emad Abdallah Turan Turan Health Group

      Bursa, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2012

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      Ayhan Kara Central Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor

      In practice since 1991

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      Tansu Gursoy Optimed International Hospital

      Tekirdag, Turkey

      Removal of spinal cord tumor

      In practice since 2009

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      Mehmet Hakan Sahin Atlas University Hospital

      Istanbul, Turkey

      Removal of spinal cord tumor

      In practice since 2010

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      Abdullah Emre Tacyildiz Optimed International Hospital

      Tekirdag, Turkey

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2012

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      Romania · 1 entries
      Specialist Clinic Operations and experience Ask about treatment
      Alexandru Cristescu Ponderas Academic Hospital

      Bucharest, Romania

      Removal of spinal cord tumor; Removal of meningioma

      In practice since 2010

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      Republic of Korea · 2 entries
      Specialist Clinic Operations and experience Ask about treatment
      Sangwon Hwang Leadheal Hospital

      Seoul, Republic of Korea

      Removal of spinal cord tumor

      In practice since 1996

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      Han Yeongmin NAEUN HOSPITAL

      Incheon, Republic of Korea

      Removal of meningioma

      In practice since 1990

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      Sources (29)

      Programmes and prices

      Lokman Hekim Istanbul Hospital · 1 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Cyst Drainage & Steroid Implementation Lokman Hekim Istanbul Hospital USD 10000Bookimed offer, Oct 2026
      What the programme includes

      Cyst Drainage & Steroid Implementation

      Included: Consultation with a neurosurgeon

      Included: Removal of spinal cord tumor

      Excluded: Airfare

      Excluded: Additional activities not included

      Read the public programme source

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      Anadolu Medical Center · 2 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Consultations + Treatment program : radiotherapy Anadolu Medical Center USD 1360Bookimed offer, Oct 2026
      What the programme includes

      Consultations + Treatment program : radiotherapy

      Included: Removal of spinal cord tumor

      Included: Transfer airport-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

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      Thoracic Intramedullary Spinal Cord Tumor Resection with Laminoplasty and Neurophysiological Monitoring Anadolu Medical Center USD 18000Bookimed offer, Oct 2026
      What the programme includes

      Thoracic Intramedullary Spinal Cord Tumor Resection with Laminoplasty and Neurophysiological Monitoring

      Included: Brain tumor removal

      Included: Brain tumor surgery

      Included: Removal of spinal cord tumor

      Included: General anesthesia

      Included: Consultation with an anesthesiologist

      Included: Medical Examination for pre-operation

      Included: Medications

      Included: Post-op medications

      Included: Electrocardiogram (ECG)

      Included: Hospitalization

      Included: Transfer airport-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Stay: 6 days in the hospital

      Additional source terms: This procedure is designed for thoracic intramedullary spinal cord tumors and performed using microsurgical techniques to safely remove the lesion while preserving spinal cord function. Thoracic laminoplasty is performed to maintain spinal stability, and continuous neurophysiological monitoring enhances surgical safety. Advanced microsurgical equipment supports controlled tumor excision, followed by structured postoperative monitoring and early recovery planning. Included Services Neurosurgery consultation and treatment planning Thoracic intramedullary tumor excision Thoracic laminoplasty (2 levels) Neurophysiological monitoring Standard pathological examination Anesthesia services All surgical materials and medications 1 night intensive care unit (ICU) stay 5 days ward hospitalization Accompanying person accommodation included

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      Valued Med Hub Hospitals · 1 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Neuromonitor-guided AVM or Tumor excision Valued Med Hub Hospitals USD 27000Bookimed offer, Oct 2026
      What the programme includes

      Neuromonitor-guided AVM or Tumor excision

      Included: Removal of spinal cord tumor

      Included: AVM Embolization

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

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      Memorial Göztepe Hospital · 4 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Convexity Tumor Resection Memorial Göztepe Hospital USD 24520Bookimed offer, Oct 2026
      What the programme includes

      Convexity Tumor Resection

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 4 days in the hospital

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      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.) Memorial Göztepe Hospital USD 26440Bookimed offer, Oct 2026
      What the programme includes

      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.)

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 3 days in the hospital

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      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy) Memorial Göztepe Hospital USD 28440Bookimed offer, Oct 2026
      What the programme includes

      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy)

      Included: Removal of spinal cord tumor

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 6 days in the hospital

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      skull base tumor Surgery Memorial Göztepe Hospital USD 40000Bookimed offer, Oct 2026
      What the programme includes

      skull base tumor Surgery

      Included: Removal of meningioma

      Excluded: Airfare

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Excluded: Transfer is not included

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      Memorial Şişli Hospital · 3 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Convexity Tumor Resection Memorial Şişli Hospital USD 24520Bookimed offer, Oct 2026
      What the programme includes

      Convexity Tumor Resection

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 4 days in the hospital

      Read the public programme source

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      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.) Memorial Şişli Hospital USD 26440Bookimed offer, Oct 2026
      What the programme includes

      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.)

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 3 days in the hospital

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      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy) Memorial Şişli Hospital USD 28440Bookimed offer, Oct 2026
      What the programme includes

      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy)

      Included: Removal of spinal cord tumor

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 6 days in the hospital

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      Memorial Bahçelievler Hospital · 3 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Convexity Tumor Resection Memorial Bahçelievler Hospital USD 24520Bookimed offer, Oct 2026
      What the programme includes

      Convexity Tumor Resection

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 4 days in the hospital

      Read the public programme source

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      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.) Memorial Bahçelievler Hospital USD 26440Bookimed offer, Oct 2026
      What the programme includes

      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.)

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 3 days in the hospital

      Read the public programme source

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      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy) Memorial Bahçelievler Hospital USD 28440Bookimed offer, Oct 2026
      What the programme includes

      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy)

      Included: Removal of spinal cord tumor

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 6 days in the hospital

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      Memorial Ataşehir Hospital · 3 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Convexity Tumor Resection Memorial Ataşehir Hospital USD 24520Bookimed offer, Oct 2026
      What the programme includes

      Convexity Tumor Resection

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 4 days in the hospital

      Read the public programme source

      Ask about treatment
      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.) Memorial Ataşehir Hospital USD 26440Bookimed offer, Oct 2026
      What the programme includes

      Parasagittal Tumor Resection (Interhemispheric, Tentorial Region, etc.)

      Included: Removal of meningioma

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 3 days in the hospital

      Read the public programme source

      Ask about treatment
      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy) Memorial Ataşehir Hospital USD 28440Bookimed offer, Oct 2026
      What the programme includes

      Removal of Lumbar Intramedullary Spinal Tumor (Including Laminectomy)

      Included: Removal of spinal cord tumor

      Included: Transfer airport-hotel-clinic-airport

      Excluded: Airfare

      Excluded: Hotel

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Stay: 6 days in the hospital

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      Ponderas Academic Hospital · 1 entries
      Public programme Clinic Recorded price Programme details Request a quote
      Complex Brain Tumor Resection Ponderas Academic Hospital USD 17909.53Bookimed offer, Oct 2026
      What the programme includes

      Complex Brain Tumor Resection

      Included: Removal of meningioma

      Excluded: Airfare

      Excluded: Additional activities not included

      Excluded: Accommodation is not included

      Excluded: Transfer is not included

      Stay: 4 days in the hospital

      Read the public programme source

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      Sources (18)

      References and further reading

      1. Brain and spinal cord tumors: surgeons
      2. Insights on Survival and Recurrence After Surgery in Malignant Meningiomas: A Systematic Review and Meta-Analysis.
      3. Laser interstitial thermal therapy for recurrent glioblastomas: a systematic review and meta-analysis.

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