{"schema_version":"bookimed.page-context.v1","id":"method-oncosurgery-op395","url":"https://hub.bookimed.com/oncologic-surgery/method-oncosurgery-op395/","json_url":"https://hub.bookimed.com/oncologic-surgery/method-oncosurgery-op395/#page-context","content_revision":"prepared-registry-v2","date_modified":"2026-10-21","language":"en","kind":"guide","title":"Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS)","summary":"Magnetic resonance-guided focused ultrasound surgery (MRgFUS) uses focused ultrasound energy to heat and destroy a targeted area of tissue, with MRI images guiding treatment. This tissue destruction is called ablation. In prostate cancer, focal treatment targets part of the prostate rather than the whole gland. MRI-guided ultrasound also includes a different technique, transurethral ultrasound ablation (TULSA); its whole-gland treatment results should not be treated as results for focal MRgFUS.","research_credit":{"name":"Yevhenii Kozlov","role":"Co-Founder of Bookimed","url":"https://us-uk.bookimed.com/ceo/kozlov/","contribution":"Research project led","assistance":"For me, helping patients find the best medical care is a personal responsibility. This guide is built by a process we designed to do the hard part — reading the research, comparing surgeons and clinics, checking real offers — and to make the result simple and clear for every patient. AI tools do much of the work; every fact links to its source."},"editorial_scope":"Source-linked research and public provider information. Individual treatment requires clinical assessment.","research_method":"How this guide is researched and compared Research project led by Yevhenii Kozlov .","sections":[{"id":"narrative-mechanism_and_choices","title":"How surgery works and how approaches differ","text":"How surgery works and how approaches differ Magnetic resonance-guided focused ultrasound surgery (MRgFUS) uses focused ultrasound energy to heat and destroy a targeted area of tissue, with MRI images guiding treatment. This tissue destruction is called ablation. In prostate cancer, focal treatment targets part of the prostate rather than the whole gland. MRI-guided ultrasound also includes a different technique, transurethral ultrasound ablation (TULSA); its whole-gland treatment results should not be treated as results for focal MRgFUS. Sources (2) The Thermal Ablation with MRgFUS: From Physics to Oncological Applications. Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","links":[{"label":"The Thermal Ablation with MRgFUS: From Physics to Oncological Applications.","url":"https://pubmed.ncbi.nlm.nih.gov/39796667/"},{"label":"Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/42056384/"}]},{"id":"narrative-indications_and_alternatives","title":"When surgery may help and what alternatives to discuss","text":"When surgery may help and what alternatives to discuss For prostate cancer, MRgFUS has mainly been studied in men whose cancer is confined to the prostate and classified as low or intermediate risk. The aim of focal treatment is to treat cancer while preserving tissue and function. MRI-guided ultrasound has also been studied in smaller groups with higher-risk cancer or cancer returning after radiotherapy. Treatment after radiotherapy has a different risk profile from first treatment. Removal of the prostate is an alternative discussed in this research, but comparisons with earlier surgical patient groups do not establish that MRgFUS is the better choice for an individual. Another cancer-related use of MRgFUS is pain relief for cancer that has spread to bone; pain relief and control of a prostate tumour are different treatment goals. Sources (2) Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review. The Thermal Ablation with MRgFUS: From Physics to Oncological Applications.","links":[{"label":"Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/42056384/"},{"label":"The Thermal Ablation with MRgFUS: From Physics to Oncological Applications.","url":"https://pubmed.ncbi.nlm.nih.gov/39796667/"}]},{"id":"narrative-outcomes_and_limits","title":"Expected outcomes and limits of the evidence","text":"Expected outcomes and limits of the evidence In men treated with focal MRgFUS for localized prostate cancer, research describes strong cancer control within the treated area, while tissue samples taken elsewhere in the prostate can still reveal cancer. The prostate evidence reviewed in 2026 consists mainly of studies without a comparison group, with short follow-up and differing treatment designs. A 2024 report described treatment of one patient with a recurrent tenosynovial giant cell tumour in the forefoot: the procedure was judged successful and no immediate complications were observed. That immediate result in one patient does not establish lasting tumour control or predict results for other cancers. Sources (2) Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review. MRgFUS ablation of a recurrent tenosynovial giant cell tumor in the foot using ExAblate 2100 system in combination with patient immobilization device.","links":[{"label":"Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/42056384/"},{"label":"MRgFUS ablation of a recurrent tenosynovial giant cell tumor in the foot using ExAblate 2100 system in combination with patient immobilization device.","url":"https://pubmed.ncbi.nlm.nih.gov/38574580/"}]},{"id":"narrative-risks","title":"Risks to discuss with your surgeon","text":"Risks to discuss with your surgeon In prostate cancer research covering both MRgFUS and TULSA, side effects were mostly mild and temporary, while serious complications were concentrated in treatment for cancer returning after radiotherapy. Cancer outside the area treated with focal MRgFUS is an important concern when there is more than one cancer focus in the prostate. Preserving urinary control and erections is an aim of tissue-preserving treatment, not a guarantee for each patient. Sources (1) Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","links":[{"label":"Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/42056384/"}]},{"id":"narrative-recovery_and_followup","title":"Recovery and follow-up care","text":"Recovery and follow-up care After focal prostate treatment, follow-up research has used systematic biopsies, which take tissue samples from different parts of the prostate. These checks have detected cancer outside the treated area even when control within that area was strong. Follow-up therefore concerns the rest of the prostate as well as the treated target. Sources (1) Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","links":[{"label":"Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/42056384/"}]},{"id":"explore","title":"Explore surgery and care teams","text":"Explore surgery and care teams Other cancers and specialized treatments: surgery and treatment options Other cancers and specialized treatments: surgeons Other cancers and specialized treatments: clinics","links":[{"label":"Other cancers and specialized treatments: surgery and treatment options","url":"https://hub.bookimed.com/oncologic-surgery/organ-special/"},{"label":"Other cancers and specialized treatments: surgeons","url":"https://hub.bookimed.com/oncologic-surgery/surgeons-organ-special/"},{"label":"Other cancers and specialized treatments: clinics","url":"https://hub.bookimed.com/oncologic-surgery/clinics-organ-special/"}]},{"id":"programmes","title":"Programmes and prices","text":"Programmes and prices Public programme Clinic Recorded price Programme details Request a quote Magnetic Resonance-guided Focused Ultrasound (MRgFUS) VM Medical Park Florya Hospital USD 1700 Bookimed offer , Oct 2026 What the programme includes Magnetic Resonance-guided Focused Ultrasound (MRgFUS) Included: Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) Excluded: Airfare Excluded: Hotel Excluded: Additional activities not included Excluded: Accommodation is not included Excluded: Transfer is not included Read the public programme source Ask about treatment Sources (1) Magnetic Resonance-guided Focused Ultrasound (MRgFUS)","links":[{"label":"VM Medical Park Florya Hospital","url":"https://hub.bookimed.com/oncologic-surgery/clinic-5613/"},{"label":"Bookimed offer","url":"https://us-uk.bookimed.com/offer-procedure/6810d8ebc2a605244a0e2fa2/"},{"label":"Read the public programme source","url":"https://us-uk.bookimed.com/offer-procedure/6810d8ebc2a605244a0e2fa2/"},{"label":"Magnetic Resonance-guided Focused Ultrasound (MRgFUS)","url":"https://us-uk.bookimed.com/offer-procedure/6810d8ebc2a605244a0e2fa2/"}],"tables":[[["Public programme","Clinic","Recorded price","Programme details","Request a quote"],["Magnetic Resonance-guided Focused Ultrasound (MRgFUS)","VM Medical Park Florya Hospital","USD 1700 Bookimed offer , Oct 2026","What the programme includes Magnetic Resonance-guided Focused Ultrasound (MRgFUS) Included: Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) Excluded: Airfare Excluded: Hotel Excluded: Additional activities not included Excluded: Accommodation is not included Excluded: Transfer is not included Read the public programme source","Ask about treatment"]]]},{"id":"research","title":"Research and sources","text":"Research and sources Sources (18) PROMISe trial: a pilot, randomized, placebo-controlled trial of magnetic resonance guided focused ultrasound for uterine fibroids. Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review. Speech Changes After Second-Side Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy: Is Intraoperative Speech Evaluation Associated With Speech Outcomes? Double lesion MRgFUS thalamotomy for essential tremor: 4.5-year outcomes and framework for assessing loss of efficacy and tremor progression. Predicting Post-Operative Side Effects in VIM MRgFUS Based on THalamus Optimized Multi Atlas Segmentation (THOMAS) on White-Matter-Nulled MRI: A Retrospective Study. Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models. Long-term outcomes and re-intervention rates in women undergoing mri-guided focused ultrasound (mrgfus) for uterine fibroids: a 7-year follow-up study. Using the Tissue Impulse Response Function to Streamline Fractionated MRgFUS-Induced Hyperthermia. MRgFUS ablation of a recurrent tenosynovial giant cell tumor in the foot using ExAblate 2100 system in combination with patient immobilization device. Ultrasmall iron oxide nanoparticles with MRgFUS for enhanced magnetic resonance imaging of orthotopic glioblastoma. Transcutaneous Ablation of Lung Tissue in a Porcine Model Using Magnetic-Resonance-Guided Focused Ultrasound (MRgFUS). Diffusion-weighted imaging as a potential non-gadolinium alternative for immediate assessing the hyperacute outcome of MRgFUS ablation for uterine fibroids. Initial outcomes and safety of MR guided focused ultrasound (MRgFUS) thalamotomy for essential tremor of the first FUS Medical Unit in Portugal. The Thermal Ablation with MRgFUS: From Physics to Oncological Applications. Evaluation of the efficacy and safety of MRI-guided focused ultrasound (MRgFUS) for focal hand dystonia: study protocol for an open-label non-randomised clinical trial. Simultaneous estimation of SAR, thermal diffusivity, and damping using periodic power modulation for MRgFUS quality assurance. Comparison of computer simulations and clinical treatment results of magnetic resonance-guided focused ultrasound surgery (MRgFUS) of uterine fibroids. Robotic system for top to bottom MRgFUS therapy of multiple cancer types.","links":[{"label":"PROMISe trial: a pilot, randomized, placebo-controlled trial of magnetic resonance guided focused ultrasound for uterine fibroids.","url":"https://pubmed.ncbi.nlm.nih.gov/26658133/"},{"label":"Oncological efficacy, functional outcomes and safety of MR-guided ultrasound ablation (MRgFUS/TULSA) for localized prostate cancer: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/42056384/"},{"label":"Speech Changes After Second-Side Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy: Is Intraoperative Speech Evaluation Associated With Speech Outcomes?","url":"https://pubmed.ncbi.nlm.nih.gov/42582188/"},{"label":"Double lesion MRgFUS thalamotomy for essential tremor: 4.5-year outcomes and framework for assessing loss of efficacy and tremor progression.","url":"https://pubmed.ncbi.nlm.nih.gov/39016204/"},{"label":"Predicting Post-Operative Side Effects in VIM MRgFUS Based on THalamus Optimized Multi Atlas Segmentation (THOMAS) on White-Matter-Nulled MRI: A Retrospective Study.","url":"https://pubmed.ncbi.nlm.nih.gov/39730158/"},{"label":"Repeated 5-aminolevulinic acid mediated sonodynamic therapy using magnetic resonance guided focused ultrasound in rat brain tumour models.","url":"https://pubmed.ncbi.nlm.nih.gov/39775160/"},{"label":"Long-term outcomes and re-intervention rates in women undergoing mri-guided focused ultrasound (mrgfus) for uterine fibroids: a 7-year follow-up study.","url":"https://pubmed.ncbi.nlm.nih.gov/39899259/"},{"label":"Using the Tissue Impulse Response Function to Streamline Fractionated MRgFUS-Induced Hyperthermia.","url":"https://pubmed.ncbi.nlm.nih.gov/39941882/"},{"label":"MRgFUS ablation of a recurrent tenosynovial giant cell tumor in the foot using ExAblate 2100 system in combination with patient immobilization device.","url":"https://pubmed.ncbi.nlm.nih.gov/38574580/"},{"label":"Ultrasmall iron oxide nanoparticles with MRgFUS for enhanced magnetic resonance imaging of orthotopic glioblastoma.","url":"https://pubmed.ncbi.nlm.nih.gov/38647018/"},{"label":"Transcutaneous Ablation of Lung Tissue in a Porcine Model Using Magnetic-Resonance-Guided Focused Ultrasound (MRgFUS).","url":"https://pubmed.ncbi.nlm.nih.gov/38668399/"},{"label":"Diffusion-weighted imaging as a potential non-gadolinium alternative for immediate assessing the hyperacute outcome of MRgFUS ablation for uterine fibroids.","url":"https://pubmed.ncbi.nlm.nih.gov/38684835/"},{"label":"Initial outcomes and safety of MR guided focused ultrasound (MRgFUS) thalamotomy for essential tremor of the first FUS Medical Unit in Portugal.","url":"https://pubmed.ncbi.nlm.nih.gov/39187258/"},{"label":"The Thermal Ablation with MRgFUS: From Physics to Oncological Applications.","url":"https://pubmed.ncbi.nlm.nih.gov/39796667/"},{"label":"Evaluation of the efficacy and safety of MRI-guided focused ultrasound (MRgFUS) for focal hand dystonia: study protocol for an open-label non-randomised clinical trial.","url":"https://pubmed.ncbi.nlm.nih.gov/37900622/"},{"label":"Simultaneous estimation of SAR, thermal diffusivity, and damping using periodic power modulation for MRgFUS quality assurance.","url":"https://pubmed.ncbi.nlm.nih.gov/37994800/"},{"label":"Comparison of computer simulations and clinical treatment results of magnetic resonance-guided focused ultrasound surgery (MRgFUS) of uterine fibroids.","url":"https://pubmed.ncbi.nlm.nih.gov/34601729/"},{"label":"Robotic system for top to bottom MRgFUS therapy of multiple cancer types.","url":"https://pubmed.ncbi.nlm.nih.gov/34996126/"}]},{"id":"request","title":"Request a treatment proposal","text":"Request a treatment proposal Share your diagnosis and reports through the Bookimed request form.","links":[]},{"id":"request-form","title":"Ask about treatment","text":"Ask about treatment What would you like help with? Answer a few questions on Bookimed, then add your contact details to request help. Privacy policy Open the Bookimed request form","links":[{"label":"Privacy policy","url":"https://us-uk.bookimed.com/page/privacy-policy/"}]}],"introduction":"Oncologic surgery guide / Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) Decision guide Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) Magnetic resonance-guided focused ultrasound surgery (MRgFUS) uses focused ultrasound energy to heat and destroy a targeted area of tissue, with MRI images guiding treatment. Research project led by Yevhenii Kozlov · Co-Founder of Bookimed Updated 21 October 2026 Sources linked throughout","related_documents":[{"id":"oncologic-surgery","title":"Oncologic surgery: explore care by organ","kind":"home","url":"https://hub.bookimed.com/oncologic-surgery/","json_url":"https://hub.bookimed.com/oncologic-surgery/page-contexts/oncologic-surgery.json"},{"id":"clinic-5613","title":"VM Medical Park Florya Hospital","kind":"clinic-profile","url":"https://hub.bookimed.com/oncologic-surgery/clinic-5613/","json_url":"https://hub.bookimed.com/oncologic-surgery/clinic-5613/#page-context"},{"id":"organ-special","title":"Other cancers and specialized treatments: surgery and treatment options","kind":"guide","url":"https://hub.bookimed.com/oncologic-surgery/organ-special/","json_url":"https://hub.bookimed.com/oncologic-surgery/organ-special/#page-context"},{"id":"surgeons-organ-special","title":"Other cancers and specialized treatments: 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