{"schema_version":"bookimed.page-context.v1","id":"method-oncosurgery-op363","url":"https://hub.bookimed.com/oncologic-surgery/method-oncosurgery-op363/","json_url":"https://hub.bookimed.com/oncologic-surgery/method-oncosurgery-op363/#page-context","content_revision":"prepared-registry-v2","date_modified":"2026-10-21","language":"en","kind":"guide","title":"Mohs microsurgery","summary":"Mohs microsurgery, also called Mohs micrographic surgery, removes skin cancer while the edges of the removed tissue are examined under a microscope during the operation. This allows precise removal with checks of the tissue margins.","research_credit":{"name":"Yevhenii Kozlov","role":"Co-Founder of Bookimed","url":"https://us-uk.bookimed.com/ceo/kozlov/","contribution":"Research project led","assistance":"For me, helping patients find the best medical care is a personal responsibility. This guide is built by a process we designed to do the hard part — reading the research, comparing surgeons and clinics, checking real offers — and to make the result simple and clear for every patient. AI tools do much of the work; every fact links to its source."},"editorial_scope":"Source-linked research and public provider information. Individual treatment requires clinical assessment.","research_method":"How this guide is researched and compared Research project led by Yevhenii Kozlov .","sections":[{"id":"narrative-mechanism_and_choices","title":"How surgery works and how approaches differ","text":"How surgery works and how approaches differ Mohs microsurgery, also called Mohs micrographic surgery, removes skin cancer while the edges of the removed tissue are examined under a microscope during the operation. This allows precise removal with checks of the tissue margins. Sources (1) Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review.","links":[{"label":"Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review.","url":"https://pubmed.ncbi.nlm.nih.gov/40919776/"}]},{"id":"narrative-indications_and_alternatives","title":"When surgery may help and what alternatives to discuss","text":"When surgery may help and what alternatives to discuss Mohs is used to treat skin cancers, including basal cell carcinoma and squamous cell carcinoma. For early tumours without lymph-node involvement, treatments studied alongside Mohs include conventional surgical removal, external-beam radiation and brachytherapy, a form of radiation treatment. These are different treatment options, not automatically interchangeable choices for every tumour. Invasive melanoma requires a separate comparison. Mohs has been studied against wide local excision, which removes the tumour with a surrounding margin of tissue. Patients receiving Mohs in these studies were generally older and had thinner melanomas, so the comparisons do not establish which operation gives better outcomes for otherwise similar patients. Sources (2) Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients. Mohs micrographic surgery for the treatment of invasive melanoma: A systematic review with meta-analyses.","links":[{"label":"Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients.","url":"https://pubmed.ncbi.nlm.nih.gov/31355928/"},{"label":"Mohs micrographic surgery for the treatment of invasive melanoma: A systematic review with meta-analyses.","url":"https://pubmed.ncbi.nlm.nih.gov/38842170/"}]},{"id":"narrative-outcomes_and_limits","title":"Expected outcomes and limits of the evidence","text":"Expected outcomes and limits of the evidence For early basal cell and squamous cell skin cancers classified as T1–T2N0, meaning early tumours without lymph-node involvement, a pooled analysis included 21,371 patients across several treatments. The estimated rate of cancer returning after Mohs was 0.2% at one year, with a statistical uncertainty range of 0% to 0.6%. The 21,371 patients were the total across all treatments, not the number who had Mohs. Cancer control at one year was similar across the treatments studied. This short-term result is not a lifetime cure rate or an individual prediction. Appearance after treatment was also studied, but the Mohs evidence on cosmetic results came from only one study. Differences in which patients received each treatment and how results were reported make it difficult to conclude that one treatment gives a better cosmetic result. Sources (1) Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients.","links":[{"label":"Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients.","url":"https://pubmed.ncbi.nlm.nih.gov/31355928/"}]},{"id":"narrative-risks","title":"Risks to discuss with your surgeon","text":"Risks to discuss with your surgeon Microscopic examination during Mohs can sometimes reveal an unexpected finding separate from the original tumour. Some findings are benign, while others can change the treatment plan and require further treatment. Opioid pain medicines can lead to dependence even after a short postoperative prescription. They are not recommended as a routine prescription for every patient after Mohs surgery and reconstruction. Sources (2) Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review. Opioid Prescribing Recommendations After Mohs Micrographic Surgery and Reconstruction: A Delphi Consensus.","links":[{"label":"Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review.","url":"https://pubmed.ncbi.nlm.nih.gov/40919776/"},{"label":"Opioid Prescribing Recommendations After Mohs Micrographic Surgery and Reconstruction: A Delphi Consensus.","url":"https://pubmed.ncbi.nlm.nih.gov/32769528/"}]},{"id":"narrative-recovery_and_followup","title":"Recovery and follow-up care","text":"Recovery and follow-up care Pain relief after Mohs surgery and reconstruction does not automatically require an opioid prescription. Expert recommendations do not support prescribing these medicines routinely to everyone undergoing the procedure. Sources (1) Opioid Prescribing Recommendations After Mohs Micrographic Surgery and Reconstruction: A Delphi Consensus.","links":[{"label":"Opioid Prescribing Recommendations After Mohs Micrographic Surgery and Reconstruction: A Delphi Consensus.","url":"https://pubmed.ncbi.nlm.nih.gov/32769528/"}]},{"id":"explore","title":"Explore surgery and care teams","text":"Explore surgery and care teams Skin cancer: surgery and treatment options Skin cancer: surgeons Mohs microsurgery surgeons Skin cancer: clinics Mohs microsurgery clinics","links":[{"label":"Skin cancer: surgery and treatment options","url":"https://hub.bookimed.com/oncologic-surgery/organ-skin/"},{"label":"Skin cancer: surgeons","url":"https://hub.bookimed.com/oncologic-surgery/surgeons-organ-skin/"},{"label":"Mohs microsurgery surgeons","url":"https://hub.bookimed.com/oncologic-surgery/surgeons-method-oncosurgery-op363/"},{"label":"Skin cancer: clinics","url":"https://hub.bookimed.com/oncologic-surgery/clinics-organ-skin/"},{"label":"Mohs microsurgery clinics","url":"https://hub.bookimed.com/oncologic-surgery/clinics-method-oncosurgery-op363/"}]},{"id":"specialists","title":"Specialists and their operations","text":"Specialists and their operations Specialist Clinic Operations and experience Ask about treatment Peter Schenker Medical Center in Solingen Solingen, Germany Esophagectomy; Small intestine resection; Lumpectomy; Whipple surgery; Mohs microsurgery; Colectomy (large bowel resection); Liver resection; Rectal resection; Gastroectomy; Pancreatic cancer surgery In practice since 2007 Ask about treatment Wolfgang Schröder Helios Gesundheit Wuppertal, Germany Removal of liver cancer; Removal of colon cancer; Stomach cancer surgery; Da Vinci Robotic System; Esophagectomy; Small intestine resection; Breast cancer surgery; Lumpectomy; Hyperthermic Intraperitoneal Chemotherapy (HIPEC); Whipple surgery; Mohs microsurgery; Lung cancer surgery; Colectomy (large bowel resection); Liver resection; Rectal resection; Throat cancer operation; Gastroectomy; Pancreatic cancer surgery In practice since 2001 Ask about treatment Joan Ramon Garces Gatnau Centro Médico Teknon Barcelona, Spain Melanoma surgery; Mohs microsurgery In practice since 1986 Ask about treatment Sources (3) Peter Schenker Wolfgang Schröder Joan Ramon Garces Gatnau","links":[{"label":"","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-6594/"},{"label":"Peter Schenker","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-6594/"},{"label":"Medical Center in Solingen","url":"https://hub.bookimed.com/oncologic-surgery/clinic-268/"},{"label":"","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-12082/"},{"label":"Wolfgang Schröder","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-12082/"},{"label":"Helios Gesundheit","url":"https://hub.bookimed.com/oncologic-surgery/clinic-7769/"},{"label":"","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-304/"},{"label":"Joan Ramon Garces Gatnau","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-304/"},{"label":"Centro Médico Teknon","url":"https://hub.bookimed.com/oncologic-surgery/clinic-78/"},{"label":"Peter Schenker","url":"https://us-uk.bookimed.com/doctor/peter-schenker/"},{"label":"Wolfgang Schröder","url":"https://us-uk.bookimed.com/doctor/wolfgang-schroeder/"},{"label":"Joan Ramon Garces Gatnau","url":"https://us-uk.bookimed.com/doctor/joan-ramon-garces/"}],"tables":[[["Specialist","Clinic","Operations and experience","Ask about treatment"],["Peter Schenker","Medical Center in Solingen Solingen, Germany","Esophagectomy; Small intestine resection; Lumpectomy; Whipple surgery; Mohs microsurgery; Colectomy (large bowel resection); Liver resection; Rectal resection; Gastroectomy; Pancreatic cancer surgery In practice since 2007","Ask about treatment"],["Wolfgang Schröder","Helios Gesundheit Wuppertal, Germany","Removal of liver cancer; Removal of colon cancer; Stomach cancer surgery; Da Vinci Robotic System; Esophagectomy; Small intestine resection; Breast cancer surgery; Lumpectomy; Hyperthermic Intraperitoneal Chemotherapy (HIPEC); Whipple surgery; Mohs microsurgery; Lung cancer surgery; Colectomy (large bowel resection); Liver resection; Rectal resection; Throat cancer operation; Gastroectomy; Pancreatic cancer surgery In practice since 2001","Ask about treatment"],["Joan Ramon Garces Gatnau","Centro Médico Teknon Barcelona, Spain","Melanoma surgery; Mohs microsurgery In practice since 1986","Ask about treatment"]]]},{"id":"research","title":"Research and sources","text":"Research and sources Sources (18) Opioid Prescribing Recommendations After Mohs Micrographic Surgery and Reconstruction: A Delphi Consensus. Superficial Radiation Therapy versus Mohs Micrographic Surgery: A Systematic Review and Meta-Analysis. Mohs micrographic surgery for the treatment of invasive melanoma: A systematic review with meta-analyses. Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review. Intraoperative Immunohistochemistry During Mohs Micrographic Surgery and Staged Excision Decreases Local Recurrence Rates for Invasive Cutaneous Melanoma: A Systematic Review and Meta-Analysis. Local Recurrence Rates of Extramammary Paget Disease Are Lower After Mohs Micrographic Surgery Compared With Wide Local Excision: A Systematic Review and Meta-Analysis. Local Recurrence Rates of Malignant Melanoma After Mohs Micrographic Surgery Are Lowest With 5- to 10-mm Initial Margins: A Systematic Review and Meta-Analysis. Mohs Micrographic Surgery Is Equivalent to Nail Unit Excision or Amputation for Melanoma In Situ of the Nail Unit: A Systematic Review and Meta-Analysis. Local Recurrence of Melanoma Is Higher After Wide Local Excision Versus Mohs Micrographic Surgery or Staged Excision: A Systematic Review and Meta-analysis. Dermatofibrosarcoma Protuberans Recurrence After Wide Local Excision Versus Mohs Micrographic Surgery: A Systematic Review and Meta-Analysis. Systematic review and meta-analysis of local recurrence rates of head and neck cutaneous melanomas after wide local excision, Mohs micrographic surgery, or staged excision. Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients. The efficacy of Mohs micrographic surgery over the traditional wide local excision surgery in the cure of dermatofibrosarcoma protuberans. Atypical fibroxanthoma: Systematic review and meta-analysis of treatment with Mohs micrographic surgery or excision. Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review. Utilization of Mohs Micrographic Surgery for Benign Adnexal Tumors of the Skin: A Systematic Review. Mohs Micrographic Surgery for Penile Squamous Cell Carcinoma: A Systematic Review. Surgical outcomes of Adenoid cystic carcinoma treated with Mohs Micrographic Surgery and excision: a systematic review.","links":[{"label":"Opioid Prescribing Recommendations After Mohs Micrographic Surgery and Reconstruction: A Delphi Consensus.","url":"https://pubmed.ncbi.nlm.nih.gov/32769528/"},{"label":"Superficial Radiation Therapy versus Mohs Micrographic Surgery: A Systematic Review and Meta-Analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/41343548/"},{"label":"Mohs micrographic surgery for the treatment of invasive melanoma: A systematic review with meta-analyses.","url":"https://pubmed.ncbi.nlm.nih.gov/38842170/"},{"label":"Comparing Mohs micrographic surgery and wide local excision in the management of head and neck dermatofibrosarcoma protuberans: a scoping review.","url":"https://pubmed.ncbi.nlm.nih.gov/38146660/"},{"label":"Intraoperative Immunohistochemistry During Mohs Micrographic Surgery and Staged Excision Decreases Local Recurrence Rates for Invasive Cutaneous Melanoma: A Systematic Review and Meta-Analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/38530980/"},{"label":"Local Recurrence Rates of Extramammary Paget Disease Are Lower After Mohs Micrographic Surgery Compared With Wide Local Excision: A Systematic Review and Meta-Analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/36206405/"},{"label":"Local Recurrence Rates of Malignant Melanoma After Mohs Micrographic Surgery Are Lowest With 5- to 10-mm Initial Margins: A Systematic Review and Meta-Analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/36728060/"},{"label":"Mohs Micrographic Surgery Is Equivalent to Nail Unit Excision or Amputation for Melanoma In Situ of the Nail Unit: A Systematic Review and Meta-Analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/37249515/"},{"label":"Local Recurrence of Melanoma Is Higher After Wide Local Excision Versus Mohs Micrographic Surgery or Staged Excision: A Systematic Review and Meta-analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/34889212/"},{"label":"Dermatofibrosarcoma Protuberans Recurrence After Wide Local Excision Versus Mohs Micrographic Surgery: A Systematic Review and Meta-Analysis.","url":"https://pubmed.ncbi.nlm.nih.gov/35353755/"},{"label":"Systematic review and meta-analysis of local recurrence rates of head and neck cutaneous melanomas after wide local excision, Mohs micrographic surgery, or staged excision.","url":"https://pubmed.ncbi.nlm.nih.gov/33961921/"},{"label":"Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients.","url":"https://pubmed.ncbi.nlm.nih.gov/31355928/"},{"label":"The efficacy of Mohs micrographic surgery over the traditional wide local excision surgery in the cure of dermatofibrosarcoma protuberans.","url":"https://pubmed.ncbi.nlm.nih.gov/31692830/"},{"label":"Atypical fibroxanthoma: Systematic review and meta-analysis of treatment with Mohs micrographic surgery or excision.","url":"https://pubmed.ncbi.nlm.nih.gov/29981390/"},{"label":"Incidental Histologic Findings During Mohs Micrographic Surgery: A Systematic Review.","url":"https://pubmed.ncbi.nlm.nih.gov/40919776/"},{"label":"Utilization of Mohs Micrographic Surgery for Benign Adnexal Tumors of the Skin: A Systematic Review.","url":"https://pubmed.ncbi.nlm.nih.gov/41081546/"},{"label":"Mohs Micrographic Surgery for Penile Squamous Cell Carcinoma: A Systematic Review.","url":"https://pubmed.ncbi.nlm.nih.gov/41931646/"},{"label":"Surgical outcomes of Adenoid cystic carcinoma treated with Mohs Micrographic Surgery and excision: a systematic review.","url":"https://pubmed.ncbi.nlm.nih.gov/39893263/"}]},{"id":"request","title":"Request a treatment proposal","text":"Request a treatment proposal Share your diagnosis and reports through the Bookimed request form.","links":[]},{"id":"request-form","title":"Ask about treatment","text":"Ask about treatment What would you like help with? Answer a few questions on Bookimed, then add your contact details to request help. Privacy policy Open the Bookimed request form","links":[{"label":"Privacy policy","url":"https://us-uk.bookimed.com/page/privacy-policy/"}]}],"introduction":"Oncologic surgery guide / Mohs microsurgery Decision guide Mohs microsurgery Mohs microsurgery, also called Mohs micrographic surgery, removes skin cancer while the edges of the removed tissue are examined under a microscope during the operation. Research project led by Yevhenii Kozlov · Co-Founder of Bookimed Updated 21 October 2026 Sources linked throughout","related_documents":[{"id":"oncologic-surgery","title":"Oncologic surgery: explore care by organ","kind":"home","url":"https://hub.bookimed.com/oncologic-surgery/","json_url":"https://hub.bookimed.com/oncologic-surgery/page-contexts/oncologic-surgery.json"},{"id":"clinic-78","title":"Centro Médico Teknon","kind":"clinic-profile","url":"https://hub.bookimed.com/oncologic-surgery/clinic-78/","json_url":"https://hub.bookimed.com/oncologic-surgery/clinic-78/#page-context"},{"id":"surgeon-bookimed-6594","title":"Peter Schenker","kind":"doctor-profile","url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-6594/","json_url":"https://hub.bookimed.com/oncologic-surgery/surgeon-bookimed-6594/#page-context"},{"id":"surgeon-bookimed-12082","title":"Wolfgang 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